Complete regression of mycosis fungoides after ipilimumab therapy for advanced melanoma
نویسندگان
چکیده
CTCL: cutaneous T-cell lymphoma CTLA4: cytotoxic T-lymphocyte antigen-4 MF: mycosis fungoides INTRODUCTION Mycosis fungoides (MF) is the most common type of cutaneous T-cell lymphoma (CTCL). Immunostimulatory approaches, such as interferon administration, are well established in the treatment of CTCL. In the last years, several new antibodies that enhance the immune system activity have entered the field of cancer immunotherapy. Ipilimumab (a cytotoxic Tlymphocyte antigene4 [CTLA4]blocking antibody, Yervoy, Bristol-Myers Squibb, Princeton, NJ) was the first one of its class to receive an approval for treatment of melanoma. Whether ipilimumab might be effective in CTCL is not known.We describe a case of complete remission of cutaneous MF during ipilimumab treatment for advanced melanoma.
منابع مشابه
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